Single-center analysis of clinical features of human rhinovirus pneumonia in children in the Xiamen area
10.3760/cma.j.issn.1673-4912.2025.10.013
- VernacularTitle:厦门地区儿童人鼻病毒肺炎临床特征单中心分析
- Author:
Jinqiang ZHANG
1
;
Dequan SU
;
Lin YUAN
;
Hui YU
;
Zhiqiang ZHUO
Author Information
1. 复旦大学附属儿科医院厦门分院 厦门市儿童医院感染科，厦门市感染性疾病质量控制中心，厦门 361006
- Publication Type:Journal Article
- Keywords:
Human rhinovirus;
Children;
Pneumonia;
Mixed infections;
Severe cases
- From:
Chinese Pediatric Emergency Medicine
2025;32(10):778-782
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the detection and clinical features of human rhinovirus（HRV）infection in children from the Xiamen area.Methods:A retrospective analysis was conducted on children treated at Xiamen Children's Hospital from November 2021 to October 2022.Thirteen types of multiplex respiratory pathogen detection kits were used to screen for 13 common respiratory pathogens. Clinical data of HRV-positive hospitalized children were collected.Results:（1）Among 8 420 children with acute respiratory infections，HRV had the highest detection rate at 20.40%（1 718/8 420），followed by HMPV（10.12%），H3N2（7.46%），HRSV（6.94%），and HPIV（6.59%）.HRV was detected throughout the year，with the highest proportion in May（18.42%）.（2）Out of 1 718 children with HRV infection，863 cases were hospitalized for pneumonia（50.23%，863/1 718）.The median age of hospitalized children was 2.58（1.07，4.20）years old，with 53.77% under 3 years old.（3）The main clinical manifestations of HRV pneumonia were cough（97.68%，843/863），fever（58.05%，501/863），runny nose（57.01%，492/863），nasal congestion（36.96%，319/863），and wheezing（24.33%，210/843）. The HRV pneumonia co-infection group showed statistically significant differences in fever and hospitalization days compared to the single HRV pneumonia infection group（all P<0.05）.（4）Compared to the common pneumonia group，the severe HRV pneumonia group showed statistically significant differences in fever，runny nose，wheezing and hospitalization days the CRP, PCT, LDH levels, and the number of antibiotic applications after hospitalization（all P<0.05）. Conclusion:HRV infection is detected year-round in Xiamen，pneumonia is common，with children under 3 years old being particularly susceptible.It is important to be alert to mixed infections or severe pneumonia.Clinical treatment should avoid unnecessary antibiotic use，actively and provide appropriate treatment.
