Research progress of bile acids in children with sepsis
10.3760/cma.j.issn.1673-4912.2025.07.013
- VernacularTitle:胆汁酸在儿童脓毒症中的研究进展
- Author:
Jie ZHANG
1
;
Xiaoqing JING
1
Author Information
1. 承德医学院附属医院小儿内科 067000
- Publication Type:Journal Article
- Keywords:
Sepsis;
Bile acids;
Children
- From:
Chinese Pediatric Emergency Medicine
2025;32(7):545-549
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is a common critical illness in the pediatric intensive care unit，with a high prevalence and mortality rate，and is characterized by acute onset，rapid progression，and poor prognosis，which poses a significant challenge for the pediatric intensive care unit.Bile acids play an important role in the occurrence and development of sepsis，and are involved in the regulation of inflammation，immune function and other pathophysiological processes.Alterations in bile acids in early sepsis are associated with disease progression and prognosis.Therefore，further research on the role of bile acids in sepsis can provide new ideas for the clinical diagnosis and treatment of sepsis，and help to improve the early identification and prognosis of sepsis.This article reviewed the role of bile acids in pediatric sepsis.
