Influencing factors of median nerve entrapment syndrome in patients with diabetic peripheral neuropathy
10.3969/j.issn.1006-6187.2025.09.008
- VernacularTitle:糖尿病周围神经病变患者发生正中神经卡压综合征影响因素的研究
- Author:
Jie JIANG
1
;
Long CUI
;
Chixue FU
Author Information
1. 400060 武警重庆总队医院超声科
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Peripheral neuropathy;
Neuropathy disability score;
Median nerve entrapment syndrome
- From:
Chinese Journal of Diabetes
2025;33(9):678-682
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors of median nerve entrapment syndrome(MNES)in patients with diabetic peripheral neuropathy(DPN).Methods A total of 150 patients with type 2 diabetes mellitus(T2DM)who were hospitalized in the Department of Endocrinology in our hospital from May 2022 to May 2024 were selected and divided into the simple T2DM group,the DPN group and the combined MNES group,with 50 cases in each group.The general data,biochemical indicators and median nerve ultrasound characteristics of the three groups were compared.Logistic regression was used to analyze the influencing factors of MNES in patients with DPN.Results The DM duration,low density lipoprotein cholesterol(LDL-C),total cholesterol(TC),fasting plasma glucose(FPG),glycated albumin(GA),hemoglobin A1c(HbA1c),the transverse diameter(d1),anteroposterior diameter(d2),cross-sectional area and the proportion of blurred"sieve-like"structure,decreased nerve bundle echo,thickened epineurium,and unclear boundary with adjacent tissues in the T2DM,DPN,and MNES groups increased in turn(P<0.05),and the levels of vitamin D,glutathione(GSH)and superoxide dismutase(SOD)decreased in turn(P<0.05).The hip circumference and diastolic blood pressure in DPN and MNES groups were higher than those in T2DM group(P<0.05).Logistic regression analysis showed that the DM duration,LDL-C,TC,FPG,GA,HbA1c,GSH,SOD,d1,d2,cross-sectional area,blurred"sieve-like"structure,decreased echo of nerve tracts,thickening of the outer nerve membrane,and unclear boundaries with adjacent tissues were the influencing factors for the occurrence of MNES in patients with DPN.Conclusions The occurrence of MNES in patients with DPN is affected by multiple factors.Regular monitoring of relevant indicators and ultrasound features of the median nerve can help to identify and intervene early to delay the development of MNES in patients with T2DM.
