Incidence and influencing factors of emergence agitation after general anesthesia in patients undergoing non-cardiac surgery: a Meta-analysis
10.3760/cma.j.cn115682-20250117-00283
- VernacularTitle:全身麻醉非心脏手术患者苏醒期躁动发生率及影响因素的Meta分析
- Author:
Shen LIU
1
;
Weiying ZHANG
;
Meng XIU
;
Fei YANG
;
Minjia ZHENG
Author Information
1. 同济大学医学院，上海 200092
- Publication Type:Journal Article
- Keywords:
Emergence agitation;
General anesthesia;
Adult;
Risk factors;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2025;31(30):4127-4136
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the incidence and influencing factors of emergence agitation (EA) after general anesthesia in patients undergoing non-cardiac surgery.Methods:Literature on EA after general anesthesia in adult patients undergoing non-cardiac surgery was electronically retrieved from PubMed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure, Wanfang Data, VIP, and China Biology Medicine disc. The search period was from the establishment of the database to June 1, 2024. Two researchers independently screened literature, extracted data, conducted quality assessments, and used RevMan 5.3 to perform the Meta-analysis.Results:A total of 22 studies were included, involving 16 853 patients. Meta-analysis indicated that the incidence of EA after general anesthesia in patients undergoing non-cardiac surgery was 18.00%. Advanced age, male, high anesthesia grade, obesity, smoking, hypertension, diabetes, preoperative anxiety, preoperative benzodiazepine use, high preoperative leukocyte, low preoperative serum albumin, prolonged operative time, intraoperative hypothermia, type of surgery, inhalation anesthesia, hypoxemia during emergence, pain during emergence, indwelling urinary catheter, and indwelling drainage tube were risk factors for EA ( P<0.05). The use of dexmedetomidine during surgery and analgesic pump after surgery were protective factors for EA ( P<0.05) . Conclusions:The EA in patients undergoing general anesthesia for non-cardiac surgery is the result of multiple factors acting together. Clinical healthcare providers should enhance their ability to identify risk factors for EA and implement targeted interventions at an early stage to improve the quality of patient awakening and clinical outcomes.
