Progress in sepsis typing and treatment
10.3760/cma.j.issn.1673-4912.2025.09.009
- VernacularTitle:脓毒症分型及其治疗研究进展
- Author:
Xuying WANG
1
;
Ni YANG
1
Author Information
1. 中国医科大学附属盛京医院儿童重症监护室，沈阳 110004
- Publication Type:Journal Article
- Keywords:
Sepsis;
Typing;
Treatment;
Heterogeneity;
Omics
- From:
Chinese Pediatric Emergency Medicine
2025;32(9):684-689
- CountryChina
- Language:Chinese
-
Abstract:
The diagnosis of pediatric sepsis still has some controversies.According to the latest guidelines,it is temporarily described as a life-threatening organ dysfunction caused by the host's dysregulated response to infection.Although there is a complete diagnostic and treatment process,its high mortality rate has always been a problem that plagues clinicians.While the diagnosis of adult sepsis is clear,treatment outcomes remain unsatisfactory.The reason lies in the high heterogeneity of sepsis itself,and the same set of diagnostic and treatment methods are not suitable for all patients.Therefore,researchers try to find the rules to classify sepsis.Compared with adults,pediatric sepsis has a more complex pathophysiological mechanism,and the progress of typing research is relatively slow.This review summarized recent advancements in the field by comparing the typing and treatment research of both pediatric and adult sepsis.
