Transurethral 450 nm semiconductor blue laser vaporization enucleation versus transurethral resection in the treatment of non-muscle invasive bladder cancer
10.3969/j.issn.1009-8291.2025.09.006
- VernacularTitle:经尿道450nm蓝激光膀胱肿瘤汽化剜除术与经尿道膀胱肿瘤电切术治疗非肌层浸润性膀胱癌的疗效及安全性比较("大家泌尿网"观看手术视频)
- Author:
Fanzhuo TU
1
;
Zhaolian SHI
;
Yuting YANG
;
Quan DU
;
Chao MAN
;
Yongwei ZHAO
Author Information
1. 泰安市中心医院迎胜院区泌尿肾病激光治疗中心,山东泰安 271000
- Publication Type:Journal Article
- Keywords:
transurethral 450 nm semiconductor blue laser bladder tumor vaporization and enucleation;
transurethral resection of bladder tumor;
non-muscle invasive bladder cancer
- From:
Journal of Modern Urology
2025;30(9):755-759
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical efficacy and safety of transurethral 450 nm semiconductor blue laser vaporization enucleation and transurethral resection of bladder tumor(TURBT)in the treatment of non-muscle invasive bladder cancer(NMIBC).Methods The clinical data of 85 NMIBC patients undergoing surgical treatment at Yingsheng Branch of Taian Central Hospital during Dec.2022 and Feb.2024 were retrospectively collected.The patients were divided into the blue laser group(n=40)and TURBT group(n=45).The operation time,intraoperative blood loss,postoperative bladder irrigation time,postoperative catheter indwelling time,postoperative hospital stay,intraoperative complications,wound healing 3 and 6 months after operation,and tumor recurrence 1 year after operation were compared between the two groups.Results Patients in both groups successfully completed the operation without blood transfusion or conversion to open surgery.Compared with the TURBT group,the blue laser group had shorter operation time[(23.68±9.98)min vs.(29.11±14.27)min],less blood loss[(1.43±0.87)g/L vs.(3.27±0.96)g/L],and shorter postoperative bladder irrigation time[0.5(0.5,0.5)d vs.0.5(0.5,1.5)d](P＜0.05).No cases developed obturator nerve reflexes in the blue laser group,but 7 cases in the TURBT group(P＜0.05).Three months after operation,the bladder wounds healed in 24 cases in the blue laser group,but only in 7 cases in the TURBT group(P＜0.01).Conclusion Compared with TURBT,transurethral 450 nm semiconductor blue laser vaporization enucleation for the treatment of NMIBC can shorten the operation time,reduce the amount of bleeding,shorten the postoperative healing time,and cause fewer complications.It is a safe and efficient minimally invasive surgery.
