Comparison of the Effect of Intermittent Sighing and Progressive Lung Recruitment Strategy on the Improvement of Respiratory Work Load and Oxygenation Index in Patients with ARDS Related to Lung Collapse
10.13241/j.cnki.pmb.2025.18.016
- VernacularTitle:间歇性叹息与渐进式肺复张策略对肺萎陷相关ARDS患者呼吸功负荷与氧合指数改善效果的比较
- Author:
Wei-wei MAO
1
;
Wei-sheng FENG
;
Yi BO
;
Li-li ZHAO
;
Ya-song LANG
Author Information
1. 连云港市中医院(南京中医药大学连云港附属医院)急诊科 江苏连云港 222000
- Publication Type:Journal Article
- Keywords:
Acute respiratory distress syndrome;
Lung collapse;
Intermittent sighing;
Progressive lung retraction;
Respiratory work load;
Oxygenation index
- From:
Progress in Modern Biomedicine
2025;25(18):2996-3002,2902
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the differences in respiratory work load and oxygenation index improvement between intermittent sighing and progressive lung retraction strategies in patients with acute respiratory distress syndrome(ARDS)related to lung collapse.Methods:Sixty patients with ARDS related to lung collapse admitted from January 2020 to January 2024 were selected and divided into intermittent sighing group(IS group,n=30)and progressive lung re-expansion group(PLR group,n=30)according to different treatment methods.The IS group used an intermittent sighing ventilation mode,while the PLR group adopted a progressive lung re-expansion strategy.The changes in respiratory work load indicators[including work of breathing(WOB),maximum inspiratory pressure(Pmax),transcutaneous oxygen saturation(SpO2)],oxygenation index(PaO2/FiO2),lung compliance(Cst),and mechanical ventilation-related parameters were compared before and after treatment in both groups.Results:After treatment,the respiratory work load was significantly reduced in both groups,with a more pronounced decrease in WOB in the PLR group(P＜0.05);both groups showed significant improvements in oxygenation index,but the degree of improvement was more marked in the PLR group(P＜0.01);lung compliance improved more markedly in the PLR group(P＜0.05);the PLR group had significantly shorter mechanical ventilation time and ICU stay compared to the IS group(P＜0.05).Conclusions:The progressive lung recruitment strategy is better than the intermittent sighing ventilation in improving the respiratory work load,oxygenation index and lung compliance of patients with ARDS related to lung collapse.It can shorten the mechanical ventilation time and ICU hospital stay more effectively,which is worth clinical promotion and application.
