Effect of Modified Autologous Skull Defect Repair in Patients with Traumatic Brain Injury and its Influence on Neurological Function and Living Ability
10.13241/j.cnki.pmb.2025.18.010
- VernacularTitle:改良自体颅骨缺损修补术在创伤性脑损伤患者中的应用效果及对神经功能、生活能力的影响
- Author:
Bin WANG
1
;
Jin ZHU
1
;
Biao YUAN
1
;
Yu-ping TANG
1
;
Yang SHEN
1
;
Xian-jun ZHANG
1
Author Information
1. 毕节市大方县人民医院神经外科 贵州毕节 551600
- Publication Type:Journal Article
- Keywords:
Modified autologous;
Skull defect repair;
Traumatic brain injury;
Neurological function;
Living ability
- From:
Progress in Modern Biomedicine
2025;25(18):2949-2955
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect of modified autologous skull defect repair in patients with traumatic brain injury and its influence on neurological function and living ability.Methods:104 patients with traumatic brain injury who were admitted to our hospital from March 2022 to August 2024 were included,they were divided into Group A[37 cases,poly ether ether ketone(PEEK)skull defect repair],Group B(35 cases,traditional titanium mesh skull defect repair),and Group C(32 cases,modified autologous skull defect repair).Perioperative indicators,neurological function,activity of daily living,quality of life,satisfaction,and incidence of postoperative complications were compared among three groups.Results:There were no differences in the operation time,operation blood loss and postoperative hospital stay among the three groups(P＞0.05).The hospitalization costs of Group A,Group B and Group C decreased successively(P＜0.05).Activity of Daily Living(ADL)scores at 3 and 6 months after surgery increased among three groups,while National Institutes of Health Stroke Scale(NIHSS)scores decreased(P＜0.05).There was no significant difference in physiological function,social function,psychological function,and material life among the three groups at 6 months after surgery(P＞0.05).The overall satisfaction rate in Group C was higher than that of Group A and Group B(P＜0.05).The overall incidence of complications in Group C was lower than that in Group A and Group B(P＜0.05).Conclusion:PEEK,traditional titanium mesh,and modified autologous skull are used in skull defect repair,operation time,operation blood loss and postoperative hospital stay are comparable,they can also reduce neurological function damage,improve living ability,and enhance the quality of life of patients,however,PEEK is relatively expensive,the satisfaction of traditional titanium mesh is low,andincidence of postoperative complications are relatively high.
