Comparative study of selective transurethral plasma kinetic resection of the prostate and transurethral holmium laser enucleation of the prostate for residual urine volume, maximum flow rate and urethral stricture in patients with diabetes benign prostatic hyperplasia
10.3760/cma.j.cn115455-20240410-00316
- VernacularTitle:选择性经尿道等离子前列腺切除术与经尿道前列腺钬激光剜除术对伴糖尿病良性前列腺增生患者残余尿量、最大尿流率及尿道狭窄的对比研究
- Author:
Yuejun CHEN
1
;
Junjie HU
1
;
Xiaoyuan XU
1
Author Information
1. 兰溪市人民医院泌尿外科，兰溪 321100
- Publication Type:Journal Article
- Keywords:
Prostatic hyperplasia;
Diabetes mellitus;
Selective transurethral plasma kinetic resection of the prostate;
Transurethral holmium laser enucleation of th
- From:
Chinese Journal of Postgraduates of Medicine
2025;48(8):720-723
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application value of selective transurethral plasma kinetic resection of the prostate (PKRP) and transurethral holmium laser enucleation of the prostate (HoLEP) in the treatment of diabetes benign prostatic hyperplasia (BPH).Methods:A total of 114 patients with diabetes BPH diagnosed and treated in Lanxi People′s Hospital from September 2020 to September 2023 were retrospectively selected and divided into resection group and enunciation group according to the operation method, with 57 cases in each group. The resection group received selective PKRP and the enucleation group received HoLEP. Preoperative and postoperative stress response indexes were compared between the two groups, as well as urodynamics indexes and complications before and 3 months after surgery.Results:The quality of prostatectomy in the enucleation group was higher than that in the resection group : (39.68 ± 3.02) g vs. (30.25 ± 2.84) g; the operation time, intraoperative blood loss, bladder irrigation time and hospital stay in the enucleation group were lower than those in the resection group: (63.84 ± 5.44) min vs. (72.58 ± 11.33) min, (62.38 ± 15.84) ml vs. (89.54 ± 17.91) ml, (1.84 ± 0.71) d vs. (2.35 ± 0.80) d, (4.98 ± 1.16) d vs.(5.64 ± 1.05) d, there were statistical differences ( P<0.05). The levels of serum cortisol (COR) and norepinephrine (NE) in the enucleation group at 1, 3 d after surgery were lower than those in the excision group [1 d after surgery: (279.76 ± 17.82) ng/L vs. (289.51 ± 18.37) ng/L, (287.44 ± 26.51) ng/L vs. (300.47 ± 28.35) ng/L; 3 d after surgery: (236.58 ± 15.98) ng/L vs. (247.46 ± 16.47) ng/L, (269.13 ± 23.51) ng/L vs. (278.76 ± 25.62) ng/L, there were statistical differences ( P<0.05). Three months after surgery, the maximum urine flow rate in the enucleation group was higher than that in the excision group : (21.51 ± 3.82) ml/s vs. (18.74 ± 4.17) ml/s, and the residual urine volume (RUV) was lower than that in the excision group : (8.47 ± 3.06) ml vs. (10.25 ± 2.43) ml, there were statistical differences ( P<0.05). There was no significant difference in the incidence of urethral stricture and urinary incontinence between the two groups ( P>0.05). Conclusions:HoLEP for the treatment of diabetes BPH can reduce stress response, promote disease recovery, improve urodynamics, and has a safety comparable to that of selective PKRP.
