Progress in experimental models of viral myocarditis
10.3969/j.issn.1000-4718.2025.04.019
- VernacularTitle:病毒性心肌炎实验模型的研究进展
- Author:
Yi XU
1
;
Zhen LUO
;
Jieyu YOU
;
Xianwu LAN
;
Shaorong WU
Author Information
1. 暨南大学附属第一医院,广州华侨医院心血管内科,广东 广州 510630
- Publication Type:Journal Article
- Keywords:
viral myocarditis;
experimental model;
animal model;
model application
- From:
Chinese Journal of Pathophysiology
2025;41(4):783-790
- CountryChina
- Language:Chinese
-
Abstract:
Viral myocarditis is a myocardial disease resulting from various viral infections.Due to the com-plexity of its pathogenesis,effective prevention and treatment options are currently lacking.Establishing appropriate ex-perimental models is crucial for studying the pathogenic mechanisms,disease progression,early diagnosis,and the devel-opment of new drugs and therapies for viral myocarditis.This article reviews the construction methods,research advance-ments,and applications of common experimental models of viral myocarditis,which range from cell models to small ani-mal models,including mice,hamsters,and rabbits,as well as larger animals such as pigs and non-human primates.Ad-ditionally,we summarize and discuss future research directions,providing a theoretical foundation and technological guid-ance for the prevention and treatment of viral myocarditis in clinical settings.
