Progress in treatment of diabetes mellitus
10.3969/j.issn.1000-4718.2025.04.016
- VernacularTitle:糖尿病治疗的研究进展
- Author:
Yulei CHEN
1
;
Wenhui LEI
;
Ning ZHONG
;
Qiaoqin CHEN
;
Lingjing ZHANG
;
Tengchuan JIN
;
Minjie CAO
Author Information
1. 集美大学海洋食品与生物工程学院,福建 厦门 361021
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
antidiabetics;
antibody;
stem cells
- From:
Chinese Journal of Pathophysiology
2025;41(4):757-765
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus is the third most prevalent disease worldwide,following cardiovascular diseases and cancer.There is no obvious symptom in the early stage of diabetes mellitus.However,in the middle and late stages,diabetes mellitus may lead to severe clinical complications such as diabetic cardiomyopathy,kidney disease,retinopathy,or neuropathy,the primary causes for diabetes-related deaths.Therefore,the early diagnosis and treatment of diabetes mellitus are of practical significance.Compared with traditional diagnostic methods including fasting blood-glucose and oral glucose tolerance tests,the measurement of glycated hemoglobin serves as a gold standard for evaluating long-term blood glucose control,due to the relative stability of glycated hemoglobin under a period of dietary and daily practice.Ear-ly treatment of diabetes mellitus may significantly improve the prognosis of patients and enhance the overall therapeutic out-come.Diet control,physical exercise,medication,as well as psychological and social supports are critical for the treat-ment of diabetes mellitus.To date,the therapeutic methods for diabetes mellitus have been constantly enriching,along with promoted drug design and development.Some emerging technologies,such as therapies using antibodies or stem cells,have been applied to treat diabetes mellitus.Hereby the latest progress in the prevention and treatment of diabetes mellitus was comprehensively reviewed,and the application of antibodies was discussed,which may provide insights into the research and development of antibody drugs for chronic human diseases including diabetes mellitus.
