Effects of intermittent theta burst stimulation of cerebellum on static balance and walking function in subacute stroke patients
10.3969/j.issn.1001-1242.2025.11.003
- VernacularTitle:小脑间歇性θ爆发式磁刺激对亚急性期脑卒中患者静态平衡和步行功能的影响
- Author:
Kai LI
1
;
Qiuhua YU
1
;
Shiyu LI
1
Author Information
1. 中山大学附属第一医院康复医学科,广东省 广州市,510080
- Publication Type:Journal Article
- Keywords:
stroke;
cerebellar;
intermittent theta burst stimulation;
balance;
walking
- From:
Chinese Journal of Rehabilitation Medicine
2025;40(11):1621-1626,1685
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of intermittent theta burst stimulation(iTBS)on the static balance and walking function in patients with subacute stroke.Method:Twenty-eight patients with subacute stroke were randomly divided into 2 groups(14 cases in the ex-perimental group and 14 cases in the control group).Both groups received rehabilitation training.The experi-mental group received 10 times iTBS targeting the lateral cerebellar region of the hemiplegic side for 2 weeks,while the control group received sham iTBS.Patients in both groups were assessed for standing or walking tasks before and after treatment.Static balance data were collected using the Prokin balance testing instrument during standing tasks.For walking tasks,gait parameters were recorded using the Vicon motion capture system.Repeated-measures ANOVA was used to compare balance and gait data between the two groups before and af-ter the treatment.Result:No significant differences were observed in baseline characteristics,balance function,or walking func-tion between the two groups before treatment(P＞0.05).After treatment,the experimental group showed signifi-cant improvements in balance function,including reduced average sway velocity of the center of pressure in the anterior-posterior direction(P＜0.001),decreased sway area of the center pressure(P＜0.001),and the shorter trajectory path length of the center pressure(P＜0.001).In contrast,the control group exhibited no sig-nificant changes(P＞0.05).Regarding walking function,the experimental group demonstrated a significant in-crease in step frequency(P＜0.001),while the control group showed no significant change(P＞0.05).Conclusion:Cerebellar iTBS can effectively enhance static balance and walking function in patients with sub-acute stroke.
