Dosimetric comparison of tomotherapy,static IMRT and VMAT techniques in radiotherapy for cervical cancer
10.3969/j.issn.1005-202X.2025.04.002
- VernacularTitle:螺旋断层放疗、静态调强放疗和容积旋转调强放疗技术在宫颈癌放疗的剂量学对比分析
- Author:
Liangqian GOU
1
;
Shuyu WU
1
;
Huaying LIAO
1
;
Yushan YANG
1
;
Guoqian ZHANG
1
;
Hui YU
1
;
Xiaohui WANG
1
;
Shuxu ZHANG
1
Author Information
1. 广州医科大学附属肿瘤医院放疗中心,广东 广州 510095
- Publication Type:Journal Article
- Keywords:
cervical cancer;
tomotherapy;
volumetric modulated arc therapy;
static intensity-modulated radiotherapy;
dosimetry
- From:
Chinese Journal of Medical Physics
2025;42(4):429-434
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the dosimetric disparities among static intensity-modulated radiotherapy(IMRT),volumetric modulated arc therapy(VMAT),and tomotherapy(TOMO)techniques in cervical cancer radiotherapy for providing data support for clinical decision-making scheme of radiotherapy.Methods The clinical data of 19 cervical cancer patients,treated at the Affiliated Cancer Hospital and Institute of Guangzhou Medical University from February to May in 2024,were analyzed.Three plans were devised for each case using IMRT,VMAT,and TOMO techniques,followed by dosimetric evaluation in terms of various metrics such as dose volume parameters of the target areas as well as organs-at-risk(OAR),conformity index(CI),homogeneity index(HI),and delivery time.Results All 3 plans met the clinical prescription requirements for the target areas.Compared with static IMRT and VMAT,TOMO had significantly lower Dmean and Dmaxof PCTV and PGTVnd.For OAR,TOMO demonstrated significant advantages over IMRT and VMAT in the Dmean of the bladder,the Dmean,Dmax,V30,V40of the rectum,the Dmean,Dmax,V20,V30of left and right femoral heads,and the Dmean,V20,V50of the pelvis(P<0.05).In addition,the TOMO group showed significantly higher CI for both PCTV and PGTVnd as compared with IMRT and VMAT groups,and lower PGTVnd HI than IMRT group(all P<0.05).Although there was trivial difference among 3 groups in term of PCTV HI,TOMO group performed slightly better than the other two groups.Notably,VMAT technique had the shortest treatment time.Conclusion In various treatment modalities for cervical cancer,TOMO is superior to IMRT and VMAT in terms of target dose coverage,OAR dose distribution,CI,and HI.However,VMAT has the highest efficiency.
