Simulation and comparative study of different modes of transcranial direct current stimulation intervention in stroke
10.3969/j.issn.1005-202X.2025.04.013
- VernacularTitle:经颅直流电刺激干预脑卒中的不同模式疗法的仿真对比
- Author:
Mengmeng LIU
1
;
Hongli YU
Author Information
1. 河北工程大学信息与电气工程学院,河北 邯郸 056038
- Publication Type:Journal Article
- Keywords:
transcranial direct current stimulation;
stroke;
realistic head model;
finite element simulation
- From:
Chinese Journal of Medical Physics
2025;42(4):510-516
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the cortical current distribution in stroke patients during anodal,cathodal and bi-hemispheric transcranial direct current stimulation(tDCS)interventions for providing a theoretical basis for the application of different modes of tDCS in the rehabilitation of stroke patients.Methods The 4 layers of head tissue structures including scalp,skull,cerebrospinal fluid and brain were reconstructed using MRI data,and assembled into a realistic head model using finite element simulation software.Then,the stroke lesion was constructed in the brain model,and the anode and cathode electrodes were constructed on the scalp model.Finally,the effective stimulation area,effective stimulation depth,and efficiency of anodal,cathodal and bi-hemispheric tDCS in the brain were simulated and analyzed.Results The results of simulation analysis showed that anodal tDCS had the strongest focusability and highest stimulation efficiency,while bipolar tDCS had the largest effective stimulation depth.In addition,the peak current densities generated by different modes of tDCS were all located at the boundary of the lesion area,and the effective stimulation areas inside the brain were also located at the lesion area.Conclusion tDCS is a promising treatment for rehabilitation following stroke.The simulation results indicate that anodal and bi-hemispheric tDCS may have superior stimulation effects than cathodal tDCS.
