Clinical efficacy of Shexiang Baoxin pill in patients with unstable angina pectoris and type 2 diabetes mellitus:A meta-analysis
10.3969/j.issn.1008-0074.2025.05.08
- VernacularTitle:麝香保心丸治疗不稳定型心绞痛合并2型糖尿病患者临床疗效的Meta分析
- Author:
Xiang GAO
1
;
Fang-yuan LIU
1
;
Xiao-zhen HAN
1
;
Dong-qian SUN
1
;
Chuan-liang LIU
1
Author Information
1. 潍坊市人民医院老年医学一科,山东潍坊 261041
- Publication Type:Journal Article
- Keywords:
Angina,unstable;
Diabetes mellitus,type 2;
Shexiang Baoxin pill
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2025;34(5):635-640
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical efficacy of Shexiang Baoxin pill in patients with unstable angina pectoris(UAP)and type 2 diabetes mellitus(T2DM)using meta-analysis.Methods:We searched the databases including Pubmed,Web of Science,EMbase,EBSCO,Cochrane,CBM,CNKI and Wanfang for randomized controlled trials(RCTs)about the therapeutic effect of Shexiang Baoxin pill on patients with UAP and T2DM from the establish-ment to January 20th,2023.RevMan 5.3 software was used to perform meta-analysis to investigate the effect of Shexiang Baoxin pill on angina improvement and blood glucose fluctuation in patients with UAP and T2DM.Results:Six eligible literatures were included,including 346 patients in Shexiang Baoxin pill group and control group respec-tively.The results of meta-analysis showed that compared to participants in control group,those in Shexiang Baox-in pill group had significantly higher clinical overall efficiency(OR=3.13,95％CI 2.01～4.89,P＜0.001),and significantly lower angina attack frequency(MD=-0.66,95％CI-0.79～-0.52,P＜0.001),duration of angi-na(MD=-3.10,95％CI-4.11～-2.09,P＜0.001),and 2-hour postprandial blood glucose(MD=-1.79,95％CI-2.00～-1.57,P＜0.001).Conclusion:Shexiang Baoxin pill could improve clinical overall efficiency,an-gina attack frequency and duration,and reduce 2-hour postprandial blood glucose in patients with unstable angina pectoris and type 2 diabetes mellitus.
