Health-related quality of life and influencing factors in surgical patients with echinococcosis
10.3760/cma.j.cn231583-20240611-00168
- VernacularTitle:包虫病手术患者健康相关生命质量及影响因素分析
- Author:
Jiusheng WEI
1
;
Wu LIU
1
;
Genxia GAO
1
;
Xiaoyan CHE
1
Author Information
1. 甘肃省白银市靖远县疾病预防控制中心传染病防制科，白银 730900
- Publication Type:Journal Article
- Keywords:
Surgical procedures, operative;
Echinococcosis;
Prognosis;
Quality of life
- From:
Chinese Journal of Endemiology
2025;44(6):477-483
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the health-related quality of life (HRQOL) and influencing factors of echinococcosis surgical patients included in the project management in Jingyuan County since the implementation of the Central Transfer Payment for Local Echinococcosis Prevention and Control Project (hereinafter referred to as the Echinococcosis Prevention and Control Project).Methods:Surgical patients included in the management of Echinococcosis Prevention and Control Project in Jingyuan County from January 1, 2009 to December 31, 2022 were selected as study subjects for a door-to-door questionnaire survey to collect basic information, medical treatment and diagnosis, surgical situation, postoperative follow-up and management situation, preoperative and postoperative HRQOL. Multivariate logistic regression was employed to analyze the influencing factors of HRQOL in echinococcosis surgical patients.Results:A total of 111 echinococcosis patients undergoing surgery were included, with a first visit duration [ M ( Q1, Q3)] of 8.0 (5.0, 12.0) years from symptom onset to initial consultation, and a surgical treatment duration of 8.0 (5.0, 12.0) years from diagnosis to surgical intervention. The cure rate based on postoperative efficacy observation was 81.08% (90/111). There was no statistically significant differences in the distribution of preoperative and postoperative mobility, self-care, daily activities, anxiety or depression among echinococcosis patients undergoing surgery ( P > 0.05). However, significant differences were observed in the distribution of pain or discomfort and health status scores ( P < 0.001). The results of ordinal logistic regression analysis showed that preoperative age [≥61 years old, OR (95% CI) = 0.06 (0.01, 0.56), P = 0.014], preoperative concomitant hypertension (grade Ⅱ), diabetes, and heart disease [ OR (95% CI) = 13.15 (1.80, 96.13), 57.69 (2.05, 1 620.13), 10.90 (1.27, 93.90), P < 0.05], initial lesion location in the abdominal cavity and the lesion in two or more locations [ OR (95% CI) = 30.83 (1.05, 902.45), 114.25 (7.24, 1 801.75), P < 0.05] were independent influencing factors for preoperative HRQOL in patients with echinococcosis. Postoperative comorbidities of hypertension (grade Ⅱ) and diabetes [ OR (95% CI) = 42.77 (2.39, 766.21), 901.40 (4.64, 1 740.94), P < 0.05], and postoperative complications [ OR (95% CI) = 130.61 (6.27, 2 722.24), P = 0.002] were independent influencing factors for postoperative HRQOL in patients with echinococcosis. Conclusions:The health status of patients with echinococcosis has significantly improved after surgical treatment. Preoperative factors affecting HRQOL of patients with echinococcosis include age, concomitant hypertension, diabetes, heart disease, and the initial lesion location. Postoperative influencing factors include concomitant hypertension and diabetes, as well as postoperative complications.
