Elevated postprandial blood glucose alone is an influencing factor for macrosomia in pregnant women with gestational diabetes mellitus
10.3969/j.issn.1006-6187.2025.04.006
- VernacularTitle:单纯高餐后血糖的妊娠期糖尿病患者分娩巨大儿的影响因素分析
- Author:
Yingying HUAI
1
;
Xiaoyan JIN
Author Information
1. 215300 昆山市妇幼保健院妇产科
- Publication Type:Journal Article
- Keywords:
Gestational diabetes mellitus;
Macrosomia;
Postprandial blood glucose
- From:
Chinese Journal of Diabetes
2025;33(4):269-272
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors for macrosomia in pregnant women with gestational diabetes mellitus(GDM)who had isolated elevated postprandial blood glucose.Methods A total of 1188 GDM pregnant women with isolated elevated postprandial blood glucose who underwent regular prenatal examination and gave birth at the First People's Hospital of Kunshan City were enrolled in this study from January 2019 to December 2021.The age,pre-pregnancy body mass index(BMI),weight gain during pregnancy,times of pregnancy,times of delivery,fasting plasma glucose(FPG)during first trimester,glycosylated hemoglobin A1c(HbA1c)during first trimester,results of oral glucose tolerance test(OGTT),area under the curve(AUC)of OGTT time-blood glucose curve in the second trimester and neonatal birth weight were analyzed in all the participants.All the newborns were divided into macrosomia group(n=167)and non-macrosomia group(n=1021)according to the birth weight.Logistic analysis was conducted to investigate the influencing factors for macrosomia delivery in GDM pregnant women with isolated elevated postprandial blood glucose.Results The pregnancy weight gain,1,2 hPG,OGTT time blood glucose AUC,OGTT abnormal incidence,and multiparous women rate were higher in macrosomia group than in non-macrosomia group(P＜0.05).Logistic regression analysis showed that gestational weight gain,OGTT time blood glucose AUC,and multiparous women were the influencing factors for delivery of macrosomia in GDM pregnant women with isolated elevated postprandial blood glucose.Conclusions Weight gain during pregnancy,AUC of OGTT time-blood glucose curve and pregnant women are the risk factors for predicting macrosomia in GDM pregnant women with isolated elevated postprandial blood glucose.
