Research progress of the relatioship between the complement system and peri-implant bone remodeling
10.12007/j.issn.0258-4646.2025.03.014
- VernacularTitle:补体系统与种植体周围骨改建关系的研究进展
- Author:
Dongyuan WU
1
;
Siyu CHEN
1
;
Lin WU
1
;
Xiaohan LIU
1
Author Information
1. 中国医科大学口腔医学院·附属口腔医院修复科,辽宁省口腔疾病重点实验室,沈阳 110002
- Publication Type:Journal Article
- Keywords:
complement;
bone formation;
bone resorption;
implant material
- From:
Journal of China Medical University
2025;54(3):262-267
- CountryChina
- Language:Chinese
-
Abstract:
The immune microenvironment plays a crucial role in bone remodeling around implants.The complement system,a key com-ponent of the immune system,significantly influences bone formation and resorption.However,the activation of the complement system varies depending on the stages of implant placement and the types of implant materials.This review discusses the complement system,its activation pathways,its effects on bone remodeling,and the impact of various stages of implant placement and different materials on com-plement system activation.These insights would help develop strategies for promoting bone remodeling around implants through targeted regulation of the complement microenvironment in the vicinity of the implanted material.
