Dirk G?rlich and Steven L.McKnight reveal new principles of intracellular transport and cellular organization——the 2025 Lasker Basic Medical Research Award
10.3969/j.issn.1006-7795.2025.05.026
- VernacularTitle:Dirk G?rlich和Steven L.McKnight揭示细胞内运输和细胞组织新原理——2025年拉斯克奖基础医学研究奖
- Author:
Minghui ZHAO
1
;
Lin SHAN
1
Author Information
1. 首都医科大学基础医学院生物化学与分子生物学系,北京 100069
- Publication Type:Journal Article
- Keywords:
The Lasker Award;
low-complexity domains(LCDs);
nuclear pore complex;
nuclear transport;
membrane-less organelle;
neurodegenerative diseases
- From:
Journal of Capital Medical University
2025;46(5):940-944
- CountryChina
- Language:Chinese
-
Abstract:
In 2025,The Lasker Award for Basic Medical Research were awarded to two scientists,Dirk G?rlich and Steven L.McKnight,for their contributions to the structure and function of low-complexity domains(LCDs)in protein sequences.These discoveries reveal new principles of intracellular transport and cellular organization,overturning conventional knowledge and opening up novel horizons in the study of cellular transport and disease mechanisms.
