Comparison of laryngeal mask airway and endotracheal intubation general anesthesia for pulse generator implantation surgery in Parkinson's disease patients
10.3969/j.issn.1006-7795.2025.05.009
- VernacularTitle:喉罩与气管插管全麻在帕金森病患者脉冲发生器植入术中的比较
- Author:
Yuanyuan TONG
1
;
Sining XIE
1
;
Liang CHEN
1
;
Xiangjiahui LI
1
;
Ruquan HAN
1
;
Wei XIONG
1
Author Information
1. 首都医科大学附属北京天坛医院麻醉科,北京 100070
- Publication Type:Journal Article
- Keywords:
Parkinson's disease(PD);
implantable pulse generator(IPG);
laryngeal mask airway(LMA);
endotracheal intubation(ETI);
general anesthesia;
deep brain stimulation
- From:
Journal of Capital Medical University
2025;46(5):820-825
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the application effects of laryngeal mask airway(LMA)general anesthesia versus endotracheal intubation(ETI)general anesthesia in Parkinson's disease(PD)patients undergoing deep brain stimulation(DBS)implantable pulse generator(IPG)surgery.Methods A retrospective analysis was conducted on 164 PD patients who underwent IPG surgery at our hospital from August 2020 to February 2021.Patients were divided into two groups based on airway management:LMA group(n=61)and ETI group(n=103).Perioperative hemodynamic parameters,including mean arterial pressure(MAP)and heart rate(HR),were observed at five time points:pre-induction(T0),post-induction(T1),skin incision(T2),extubation(T3),and post-anesthesia care unit(PACU)admission(T4).Key outcomes,such as extubation time,intraoperative hypoxia events,LMA-to-ETI conversion rate,and postoperative complications(respiratory depression,pneumonia),were compared between the two groups.Results The LMA group had a significantly lower body mass index than the ETI group[(22.75±3.11)kg/m2 vs(23.85±3.49)kg/m2,P=0.039],while the other baseline characteristics were comparable.After induction,the LMA group exhibited a less decrease in MAP[(85.46±11.63)mmHg vs(74.13±11.78)mmHg in the ETI group,P<0.001].At extubation,the ETI group showed higher MAP[(98.27±13.78)mmHg vs(89.66±10.50)mmHg in the LMA group,P<0.001].The intraoperative use of vasoactive drugs was significantly lower in the LMA group(3.3%)than that in the ETI group(13.6%,P=0.032).The mean extubation time was shorter in the LMA group[(8.43±5.25)min vs(14.28±7.66)min in the ETI group,P<0.001].No intraoperative hypoxia or LMA-to-ETI conversion events occurred in either group.Postoperative respiratory depression and pneumonia rates showed no statistically significant differences between the groups.Conclusion LMA general anesthesia can be safely applied in PD patients undergoing DBS IPG implantation.It shortens extubation time,reduces the use of vasoactive drugs,and does not increase the risk of intubation-related complications.
