Advances in the etiology,diagnosis,and treatment of exocrine pancreatic insufficiency
10.7659/j.issn.1005-6947.240517
- VernacularTitle:胰腺外分泌功能不全的病因、诊断及治疗进展
- Author:
Chengji TANG
1
;
Jia ZHOU
;
Yinghui SONG
;
Sulai LIU
Author Information
1. 湖南师范大学附属第一医院(湖南省人民医院)肝胆外科/湖南省胆道疾病研究中心,湖南 长沙 410005
- Publication Type:Journal Article
- Keywords:
Exocrine Pancreatic Insufficiency/diag;
Exocrine Pancreatic Insufficiency/ther;
Review
- From:
Chinese Journal of General Surgery
2025;34(3):572-578
- CountryChina
- Language:Chinese
-
Abstract:
Exocrine pancreatic insufficiency(EPI)is a condition caused by a reduction in the secretion or activity of pancreatic juice and its digestive enzymes,particularly pancreatic lipase.EPI can lead to symptoms such as abdominal pain,bloating,steatorrhea,malnutrition,and weight loss,and may even increase the risk of osteoporosis and cardiovascular diseases.Diagnosis mainly relies on direct and indirect functional tests,while treatment is centered on pancreatic enzyme replacement therapy combined with comprehensive management strategies.This article summarizes the research progress on the definition,common causes,diagnostic methods,treatment,and prevention strategies of EPI,aiming to provide insights for optimizing its diagnosis and management.
