Investigation and analysis of blood lipid levels in population of health check-up in Hangzhou
10.13602/j.cnki.jcls.2025.04.11
- VernacularTitle:杭州地区体检健康人群血脂水平调查
- Author:
Xiaojuan JIANG
1
;
Lina FAN
;
Dagan YANG
Author Information
1. 浙江中医药大学医学技术与信息工程学院,杭州 310053;杭州市余杭区第一人民医院检验科,杭州 311113
- Publication Type:Journal Article
- Keywords:
big data;
blood lipids;
reference intervals;
clinical decision
- From:
Chinese Journal of Clinical Laboratory Science
2025;43(4):296-299
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the blood lipid levels in the population undergoing physical check-up population in Hangzhou dis-trict using the laboratory Big Data for providing references in disease prevention.Methods The test results of blood lipid levels of the individuals undergoing health check-up at a certain hospital from January 2022 to October 2023 were collected,excluding the abnormal positive resultss.SPSS 25.0 software was used to calculate the median(M),25th percentile(P25)and 75 Percentile(P75)grouped by gender and age in 10-year intervals.TMC was used to calculate 2.5th percentile(P25)and 97.5th percentile(P97 5),and GAMLSS was used to draw the age-continuous percentile charts.Results Gender differences in blood lipid levels were observed.The levels of total cholesterol(TC),triglycerides(TG),and low-density lipoprotein cholesterol(LDL-C)in males were higher than those of fe-males in the age of 19 to 49 groups.However,the levels of TC and LDL-C in females were higher than those of males in the age of 50 to 90 groups.TG levels in females were higher than those of males in the age of 60 to 90 groups.High-density lipoprotein cholesterol(HDL-C)levels in females were higher than those in males.TG level in males at ages of 40 to 49 reached peak,while females reached the peak of TG level at ages of 70 to 79.The LDL-C level in males at ages 40 to 49 reached the peak,while females reached the peak of LDL-C level at ages 60 to 69.Blood lipid levels were associated with age.The levels of TG,TC in female and LDL-C in female showed particularly significant changes,first increasing and then decreasing with age.Conclusion Blood lipid levels are closely relat-ed to gender and age.Personalized lipid management should be conducted,considering the factors of gender and age.