The study on PAOO minimally invasive versus traditional surgery in accelerating orthodontic tooth movement and its mecha-nisms
10.13591/j.cnki.kqyx.2025.11.003
- VernacularTitle:PAOO微创术式与传统术式促进正畸牙移动效果及生物学机制研究
- Author:
Hao LIU
1
;
Wenjing PENG
;
Qiuying GAO
;
Jiabin XU
;
Gang LIU
;
Shaoyue ZHU
Author Information
1. 徐州医科大学附属口腔医院口腔正畸科,江苏徐州(221002)
- Publication Type:Journal Article
- Keywords:
PAOO;
corticotomy;
accelerated orthodontics;
bone remodeling
- From:
STOMATOLOGY
2025;45(11):813-818
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the periodontally accelerated osteogenic orthodontics(PAOO)effects of corticotomy with full mu-coperiosteal flap(flapped corticotomy)and corticotomy-only on accelerating orthodontic tooth movement.Methods A total of 60 healthy male SD rats(weighing 180-200 g)were selected and randomly divided into three groups.There were 20 rats each in the flapped corticotomy group,the corticotomy-only group,and the control group.After applying orthodontic instruments,5 rats each in the surgical group and the control group were killed by excessive anesthesia on 0,1,3,and 7 days after tooth movement.The tooth move-ment distances of the rats in the control group and the experimental group were counted,and immunohistochemical staining was per-formed to observe the corresponding molecular biological changes.Results There was no significant difference in accelerating ortho-dontic tooth movement between the flapped corticotomy group and the corticotomy-only group.Compared with traditional orthodontic tooth movement,both the flapped corticotomygroup and the corticotomy-only group could bring an increase in the expression of RANKL on the pressed periodontal side while there was no significant difference between the two experimental groups.Both the flapped corticot-omy and non-flapped corticotomy could enlarge the area of tissue formation in the periodontal tension zone,and still there was no signif-icant difference between the two surgical methods.Compared with traditional orthodontic tooth movement,both the flapped corticotomy group and the corticotomy-only group could lead to an increase in ALP,OCN and OPN expression on the periodontal tension zone.Conclusion Both flapped corticotomy and corticotomy play a significant role in accelerating orthodontic tooth movement and promoting alveolar bone formation in the early stage.Both surgical methods of PAOO can provide more efficient and stable biological support for orthodontic treatment.
