Predictive Value of NLR,PCT and Ca on the Prognosis of Severe Pneumonia
10.11969/j.issn.1673-548X.2025.02.028
- VernacularTitle:NLR、PCT及Ca对重症肺炎预后的预测价值
- Author:
Yangyang SUN
1
;
Song PENG
Author Information
1. 233030 蚌埠医科大学研究生院
- Publication Type:Journal Article
- Keywords:
Severe pneumonia;
Neutrophil-to-lymphocyte ratio;
Procalcitonin;
Blood calcium concentration;
Severity
- From:
Journal of Medical Research
2025;54(2):177-181
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predictive value of neutrophil-to-lymphocyte ratio(NLR),procalcitonin(PCT)and serum calcium(Ca)on the prognosis of patients with severe pneumonia.Methods The clinical data of 182 SP patients admitted to Hefei First People's Hospital from January 2020 to September 2023 were retrospectively analyzed.According to the prognosis within 28days of admis-sion,they were divided into survival group(n=116)and death group(n=66).Binary Logistic regression analysis was used to analyze the related factors of poor prognosis in SP patients.Receiver operating characteristic(ROC)curve was used to analyze the predictive val-ue of NLR,PCT and Ca on the prognosis of SP.Results The age,incidence of hypertension,cerebrovascular disease and acute physiol-ogy and chronic health evaluation Ⅱ score(APACHE Ⅱ)in the death group were significantly higher than those in the survival group(P＜0.05).The levels of d-dimer(D-D),N-terminal pro-brain natriuretic peptide(NT-proBNP),NLR and PCT in the death group were higher than those in the survival group(P＜0.05).The platelet count(PLT),serum albumin(ALB)and Ca were lower than those in the survival group(P＜0.05).NLR,PCT,ALB,NT-proBNP and Ca were independent risk factors for death in SP patients(P＜0.05).The area under the curve(AUC)of NLR,PCT and Ca in predicting the prognosis of SP were 0.902,0.874 and 0.890,re-spectively(P＜0.05),and the combined AUC of the three was 0.976(95％CI:0.943-0.993).Conclusion NLR,PCT and Ca have certain predictive value for the prognosis of SP patients,and the combination of the three has the best predictive effect on SP.
