Correlation between Nap Frequency and Sleep Duration and Carotid Atherosclerosis in Middle-aged and Elderly People in Guangzhou
10.11969/j.issn.1673-548X.2025.02.011
- VernacularTitle:广州市中老年人午睡频率和睡眠时长与颈动脉粥样硬化的相关性研究
- Author:
Yongqi LI
1
;
Weisen ZHANG
;
Chaoqiang JIANG
Author Information
1. 510080 广州,中山大学公共卫生学院流行病学系
- Publication Type:Journal Article
- Keywords:
Nap frequency;
Sleep duration;
Carotid atherosclerosis;
Middle-aged and elderly people in Guangzhou
- From:
Journal of Medical Research
2025;54(2):64-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between nap frequency and sleep duration and the risk of carotid atherosclerosis(CAS)in the middle-aged and elderly people in Guangzhou.Methods A retrospective study was conducted to select 1170middle-aged and elderly patients over 50 years who were enrolled in"Guangzhou Biobank Cohort-Cardiovascular Disease Subcohort"from Sep-tember 2006 to March 2008.The general data of the subjects were collected,and the intima-media thickness of common carotid artery,CCA-IMT was measured by color Doppler ultrasound.Logistic regression analysis was used to evaluate the correlation between nap fre-quency and sleep duration and the risk of CAS.Results After adjusting for potential confounding factors such as gender,age,body mass index(BMI),waist-to-hip ratio(WHR),physical activity level,smoking,alcohol consumption,and diabetes,the study found that compared with those who never nappers,Daily nappers had a higher risk of CAS[adjusted Exp(β)=2.095,95％CI:1.823-2.407,P＜0.001].In addition,this study observed a"U-shaped"association between sleep duration and CAS prevalence.Further studies found that compared with those who slept for 6h per day,those who slept for ≤5h,8h and≥10h had a significantly increased risk of CAS(adjusted OR=1.420,95％CI:1.117-1.805,P＜0.001;OR=1.356,95％CI:1.142-1.610,P＜0.001;OR=1.537,95％CI:1.156-2.044,P＜0.01).Conclusion Daily napping and short or long sleep duration may increase the risk of CAS.It is recommen-ded to reduce the nap frequency and maintain the appropriate sleep duration in order to reduce the incidence of CAS.
