Association of unhealthy dietary habits with cardiovascular disease and mortality in Chinese residents
10.16352/j.issn.1001-6325.2025.12.1626
- VernacularTitle:中国居民不健康饮食与心血管病及死亡的关联性分析
- Author:
Xinyue LANG
1
;
Huihan YANG
;
Lei LAN
;
Guoliang HAN
;
Bo HU
;
Zhiguang LIU
Author Information
1. 首都医科大学附属北京安贞医院 药事部临床试验机构,北京 100029
- Collective Name:on behalf of PURE-China investigators
- Publication Type:Journal Article
- Keywords:
unhealthy diet;
all-cause death;
cardiovascular diseases
- From:
Basic & Clinical Medicine
2025;45(12):1626-1631
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the potential impact of unhealthy diets on cardiovascular diseases and all-cause mortality.Methods This study included the individuals aged 35-70 years from 45 cities and 70 rural communities across 12 provinces in China,as part of the Prospective Urban Rural Epidemiology(PURE)study.Dietary habits were assessed using a food frequency questionnaire.The dietary health status was scored using the Alternative Healthy Eating Index(AHEI),with participants in the lowest tertile of AHEI being categorized into the unhealthy diet group,while others were classified as the healthy diet group.The primary endpoints included major cardiovas-cular diseases(myocardial infarction,stroke,or heart failure)and all-cause mortality.Cox proportional hazard models were used to estimate hazard ratios(HR)for each group.Results A total of 40 925 participants were in-cluded in the study,with a median follow-up time of 11.9 years(interquartile range 9.6-12.6 years).During this period,2 066 deaths and 3 099 cases of major cardiovascular diseases were reported.The results showed that un-healthy diet increased the risk of major cardiovascular diseases by 10%(HR=1.10,95%CI:1.02-1.20,P＜0.05)and all-cause mortality by 7%(HR=1.07,95%CI:1.00-1.18,P＜0.05).Among male residents,un-healthy diet did not increase the risk of major cardiovascular diseases or all-cause mortality.However,among female residents,those with an unhealthy diet had a higher risk of major cardiovascular diseases(HR=1.12,95%CI:1.00-1.25,P＜0.05)and all-cause mortality(HR=1.26,95%CI:1.08-1.46,P＜0.05)compared to those with a healthy diet.Conclusions Unhealthy diet increases the risk of major cardiovascular diseases and all-cause mortality,particularly among women.There is a need to raise awareness about healthy dietary to prevent death and the occurrence of major cardiovascular diseases.
