The immunoregulatory mechanisms of myeloid cells in ocular tissues and their pathological association with diseases
10.13389/j.cnki.rao.2025.0172
- VernacularTitle:眼中髓样细胞的免疫调控机制及其与疾病病理关联
- Author:
Lulu BAO
1
;
Yang LÜ
Author Information
1. 730000 甘肃省兰州市,甘肃中医药大学第一临床医学院;730050 甘肃省兰州市,中国人民解放军联勤保障部队第九四○医院眼科中心
- Publication Type:Journal Article
- Keywords:
dendritic cell;
plasmacytoid dendritic cell;
macrophages;
microglia;
neutrophils;
mast cells;
neuroim-mune interactions
- From:
Recent Advances in Ophthalmology
2025;45(12):1003-1008
- CountryChina
- Language:Chinese
-
Abstract:
The immunoregulatory mechanisms of myeloid cells in the eye have become a research hotspot in recent years.By dynamically regulating the immune microenvironment,they play a key role in maintaining intraocular homeostasis and repairing pathological damage,while also participating in certain disease processes.This article reviews the mecha-nisms of action and potential therapeutic strategies of major myeloid cells(including dendritic cells,macrophages,micro-glia,neutrophils,and mast cells)in corneal and retinal diseases.It also explores the characteristics of neuroimmune inter-actions in the cornea and the role of microglia in maintaining retinal homeostasis.
