Pharmacological advances in pharmacological research on the treatment of dry age-related macular degeneration with traditional Chinese medicine
10.13389/j.cnki.rao.2025.0168
- VernacularTitle:中药治疗干性年龄相关性黄斑变性药理研究进展
- Author:
Siya ZHANG
1
;
Yu PEI
;
Xi CHEN
;
Li PAN
;
Ge ZHANG
;
Yuanchen DING
;
Meihui WEI
;
Wei SHI
Author Information
1. 210000 江苏省南京市,南京中医药大学第一临床医学院
- Publication Type:Journal Article
- Keywords:
dry age-related macular degeneration;
traditional Chinese medicine;
pharmacology
- From:
Recent Advances in Ophthalmology
2025;45(12):981-985
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of age-related macular degeneration(AMD)is rising with the intensifying aging trend,be-coming a critical challenge that demands urgent solutions.Dry AMD(dAMD)accounts for approximately 80％of all AMD cases,and there is currently a lack of highly effective treatment options.In recent years,traditional Chinese medicine(TCM)has been proven to effectively treat dAMD through actions such as antioxidation,anti-apoptosis,anti-inflammation,and lipid-lowering.By reviewing domestic and international literature,this article discusses TCM monomers,extracts,and compound formulations for dAMD,analyzing their various mechanisms.Based on traditional TCM efficacy theories and in-tegrated with modern mechanisms of action,it targets the active components of TCM to elucidate the connection between effective medicinal targets of TCM and dAMD,thereby clarifying the efficacy and scientific basis of TCM monomers,com-pounds,and extracts in treating dAMD.The aim is to provide new perspectives for the prevention and clinical treatment of dAMD.
