Effect of LASIK surgery for optimized monovision correction of age-related accommodation deficiency with myopia on regulatory function
10.3760/cma.j.cn115989-20231027-00155
- VernacularTitle:优化单眼视LASIK矫正年龄相关性调节不足伴近视对调节功能的影响
- Author:
Yan SUN
1
;
Haiyan WANG
;
Quan LIU
Author Information
1. 兰州普瑞眼视光医院，兰州 730000
- Publication Type:Journal Article
- Keywords:
Presbyopia;
Myopia;
Vision, monocular;
Age-related accommodative insufficiency;
Accommodation function;
Laser-assisted laser in situ keratomileusis
- From:
Chinese Journal of Experimental Ophthalmology
2025;43(6):535-541
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of laser-assisted laser in situ keratomileusis (LASIK) surgery for optimized monovision correction in the treatment of age-related accommodative deficiency with myopia on regulatory function.Methods:A cohort study was conducted.A total of 74 consecutive patients (74 eyes) with age-related accommodative insufficiency and myopia who underwent optimized monovision LASIK at Lanzhou Bright Eye Hospital from October 2019 to October 2021 were enrolled.Only non-dominant eye data were analyzed.Patients were randomized into a control group (37 cases, 37 eyes) treated with FS-LASIK and an optimization adjustment group (37 cases, 37 eyes) treated with Q-value adjusted monovision FS-LASIK.Preoperative and postoperative (within 1 year) data were collected for both groups, including distance visual acuity, near visual acuity, central 3 mm corneal equivalent spherical refraction (SE), anterior corneal Q-value, amplitude of accommodation (AMP), monocular positive relative accommodation (PRA), and lens thickness (LT).The differences of different indicators (AMP, PRA, LT) related to accommodation power at different time points were compared between the two groups.The correlation between near visual acuity, PRA, LT and AMP in the optimized adjustment group was analyzed.This study adhered to the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of LanZhou Bright Eye Hospital (No.LP-202302).Written informed consent was obtained from each subject.Results:There were significant overall differences in distance visual acuity, near visual acuity, Q value, and SE in non-dominant eyes at different time points in the two groups ( Ftime=244.98, 69, 843.65, 454.80; all P<0.05).There was a significant overall difference in Q value between the two groups ( Fgroup=2.49, P<0.05).Compared with preoperative, the postoperative distance visual acuity and near visual acuity of patients in both groups were improved, with an increase in Q value and a decrease in SE, with statistically significant differences (all P<0.05).One year after surgery, the near visual acuity and Q value of the optimized adjustment group were better than those of the control group, with statistically significant differences (both P<0.05).There were significant differences in AMP and PRA in non-dominant eyes at different time points between the two groups (AMP: Fgroup=19.03, P<0.05; Ftime=4.99, P<0.05.PRA: Fgroup=42.67, P<0.05; Ftime=28.64, P<0.05).At 1 month, 6 months and 1 year after surgery, AMP and PRA increased in the optimization adjustment group compared with the preoperative and control group, and the differences were statistically significant (all P<0.05).There were significant differences in LT before and after surgery in non-dominant eye between the two groups ( Ftime=4.94, P<0.05).Among them, the LT in the optimization adjustment group became thinner at different time points after surgery than before surgery, and the differences were statistically significant (all P<0.05).In the optimization adjustment group, near visual acuity at 1 year after surgery in non-dominant eye was positively correlated with AMP ( r=0.269, P<0.05), and PRA was negatively correlated with AMP ( r=-0.601, P<0.05), and preoperative LT was positively correlated with preoperative AMP ( r=0.276, P<0.05). Conclusions:Optimized monovision LASIK for the treatment of age-related accommodative insufficiency with myopia significantly improves the myopia-related accommodation parameters AMP, PRA, and LT.
