Research advances on the impact of obstructive sleep apnea on ocular fundus diseases
10.3760/cma.j.cn115989-20231124-00183
- VernacularTitle:阻塞性睡眠呼吸暂停对眼底疾病影响的研究进展
- Author:
Xueyi PANG
1
;
Yunshan CAO
;
Yan ZHANG
Author Information
1. 天津医科大学眼科医院 眼视光学院 眼科研究所 国家眼耳鼻喉疾病临床医学研究中心天津市分中心 天津市视网膜功能与疾病重点实验室，天津 300384
- Publication Type:Journal Article
- Keywords:
Obstructive sleep apnea;
Glaucomatous optic neuropathy;
Nonarterial anterior ischemic optic neuropathy;
Diabetic retinopathy;
Central serous chorioretinop
- From:
Chinese Journal of Experimental Ophthalmology
2025;43(1):80-86
- CountryChina
- Language:Chinese
-
Abstract:
Obstructive sleep apnea (OSA) is a common sleep disorder that is closely associated with ocular fundus diseases such as glaucomatous optic neuropathy, nonarteritic anterior ischemic optic neuropathy, diabetic retinopathy, central serous chorioretinopathy and retinal vein occlusion.The main mechanisms by which OSA affects fundus diseases include intermittent hypoxia, activation of sympathetic nervous system, systemic oxidative stress, and inflammatory response, but the specific mechanisms require further investigation.The therapeutic modality such as continuous positive airway pressure can alleviate the symptoms of ocular fundus diseases in the patients with OSA and reduce the risk of disease progression.Therefore, clinicians should recognize the relationship between OSA and fundus diseases, understand the impact of OSA on these diseases, and achieve early diagnosis and treatment of the OSA-associated fundus diseases to reduce the risk of severe visual impairment and blindness.
