Clinical Parameters in the First 5 Minutes after Birth Have a Predictive Value for Survival of Extremely Preterm Infants
10.1097/FM9.0000000000000206
- VernacularTitle:Clinical Parameters in the First 5 Minutes after Birth Have a Predictive Value for Survival of Extremely Preterm Infants
- Author:
Laura TORREJÓN-RODRÍGUEZ
1
;
Álvaro SOLAZ-GARCÍA
;
Inmaculada LARA-CANTÓN
;
Alejandro PINILLA-GONZÁLEZ
;
Marta AGUAR
;
Máximo VENTO
Author Information
1. Division of Neonatology, University and Polytechnic Hospital La Fe (HULAFE), Valencia 46026, Spain
- Publication Type:Journal Article
- Keywords:
Extreme preterm;
Postnatal stabilization;
Oxygen saturation;
Heart rate;
Inspired fraction of oxygen;
Apgar score
- From:
Maternal-Fetal Medicine
2023;05(4):244-247
- CountryChina
- Language:English
-
Abstract:
Extreme preterm infants (<28 weeks' gestation) often require positive pressure ventilation with oxygen during postnatal stabilization in the delivery room. To date, optimal inspired fraction of oxygen (FiO 2) still represents a conundrum in newborn care oscillating between higher (>60%) and lower (<30%) initial FiO 2. Recent evidence and meta-analyses have underscored the predictive value for survival and/or relevant clinical outcomes of the Apgar score and the achievement of arterial oxygen saturation measured by pulse oximetry ≥85% at 5 minutes after birth. New clinical trials comparing higher versus lower initial FiO 2 have been launched aiming to optimize postnatal stabilization of extreme preterm while avoiding adverse effects of hypoxemia or hyperoxemia.
