CSOG MFM Committee Guideline: Clinical Management Guidelines for Acute Fatty Liver of Pregnancy in China (2021)

VernacularTitle:CSOG MFM Committee Guideline: Clinical Management Guidelines for Acute Fatty Liver of Pregnancy in China (2021)
Author: Ping LI ¹ ; Yaolong CHEN ; Weishe ZHANG ; Huixia YANG
Author Information

1. Department of Obstetrics, Xiangya Hospital Central South University, Changsha, Hunan 410008, China
Publication Type:Journal Article
Keywords: Fatty liver; Acute fatty liver of pregnancy; Guidelines; Classification of evidence quality and strength of recommendation
From: Maternal-Fetal Medicine 2021;03(4):238-245
CountryChina
Language:English
Abstract: Acute fatty liver of pregnancy (AFLP) is a rare but critical obstetric-specific disease with a high fatality rate, posing a serious threat to the safety of mothers and infants. These guidelines were specially formulated to standardize AFLP clinical pathways and to improve maternal and infant outcomes. Based on a two-round questionnaire survey, the guideline development team identified the following nine clinical issues that clinicians were most concerned about, and developed recommendations for each of them: prenatal outpatient screening for AFLP, diagnosis, preoperative risk assessment, delivery modes and timing, anesthesia methods, perinatal complications, selecting AFLP patients for artificial liver treatment, prognostic assessment, and monitoring during treatment. The guidelines cover the key issues related to AFLP diagnosis and treatment that concern clinicians.