Metastatic Breast Neuroendocrine Cancer in Pregnancy: A Case of an Oncologic Emergency and a Review of Literature
10.1097/FM9.0000000000000068
- VernacularTitle:Metastatic Breast Neuroendocrine Cancer in Pregnancy: A Case of an Oncologic Emergency and a Review of Literature
- Author:
De Luca CATERINA
1
;
Valentina TOSTO
;
Badr Dominique A.
;
De Luca LAURA
;
Roberta PORRECA
Author Information
1. Department of Obstetrics and Gynecology, University Hospital Santa Maria della Misericordia, Perugia 06129, Italy
- Collective Name:Di Renzo Gian Carlo
- Publication Type:Journal Article
- Keywords:
Neoplasm metastasis;
Neuroendocrine breast carcinoma;
Oncologic emergency;
Pregnancy
- From:
Maternal-Fetal Medicine
2020;02(4):248-252
- CountryChina
- Language:English
-
Abstract:
Breast neuroendocrine carcinoma is a rare entity. It constitutes less than 0.5% of breast malignancies, and is usually diagnosed in older women. The occurrence of this type in young patients during pregnancy is extremely rare. Only 2 cases were previously reported. Both were diagnosed at earlier stage with the appearance of a palpable breast mass. Hereby, we present the case of a young patient at 28 weeks’ gestation admitted for severe diffuse back pain and neurologic deficit due to spinal cord compression at the level of C5 vertebra, and nerve root compression at the level of L5 vertebrae. To the best of our knowledge, this is the first case of oncologic emergency during pregnancy due to a metastatic poorly differentiated breast carcinoma with neuroendocrine differentiation in the absence of a detectable primary focus of malignancy in the breast. We also discuss the management and the obstetrical outcome of this patient.
