Influence of Intestinal Immunity and Microecology on Concomitant Psychological Disorders in Patients With Inflammatory Bowel Disease
10.3969/j.issn.1008-7125.2024.08.008
- VernacularTitle:肠道免疫和微生态对炎症性肠病患者并发心理疾患的影响
- Author:
Ziru ZHOU
1
;
Siyuan CHEN
1
;
Qunyan ZHOU
1
;
Jing SUN
1
;
Qiang ZHAN
1
Author Information
1. 南京医科大学附属无锡人民医院消化内科(214023)
- Publication Type:Journal Article
- Keywords:
Intestinal Immunity;
Gut Microecology;
Inflammatory Bowel Disease;
Depression;
Anxiety
- From:
Chinese Journal of Gastroenterology
2024;29(8):499-504
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease(IBD)is a group of non-specific chronic gastrointestinal inflammatory diseases whose etiology is not completely clear.In recent years,the problem of IBD complicated with psychological disorders has been widely concerned,which affects the quality of life of patients,and increases the recurrence of IBD and poor prognosis.The gut-brain axis is involved in the occurrence of IBD complicated with neuropsychiatric disorders.The gut regulates brain function through the nervous system,hypothalamic-pituitary-adrenal(HPA)axis and immune system.This article reviews the relationship between intestinal immunity,intestinal microecology and psychological disorders in IBD patients,as well as the treatment of psychological disorders based on intestinal immunity and microecology,so as to provide new ideas for the diagnosis and treatment of psychological disorders in IBD.
