Ratio of right ventricular free wall longitudinal strain to pulmonary artery systolic pressure for evaluating right ventricular systolic function in patients with hypertrophic cardiomyopathy
10.13929/j.issn.1672-8475.2025.02.004
- VernacularTitle:右心室游离壁纵向应变与肺动脉收缩压比值用于评价肥厚型心肌病患者右心室收缩功能
- Author:
Ranran LIU
1
;
Xiaofei CHEN
1
;
Guozhang TANG
1
;
Xiao MA
1
;
Jianan JIANG
1
;
Xiuxiu FU
1
Author Information
1. 青岛大学附属医院心脏超声科,山东 青岛 266000
- Publication Type:Journal Article
- Keywords:
cardiomyopathy,hypertrophic;
pulmonary circulation;
hemodynamics;
echocardiography
- From:
Chinese Journal of Interventional Imaging and Therapy
2025;22(2):97-101
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of right ventricular free wall longitudinal strain(RVFWLS)to pulmonary artery systolic pressure(PASP)ratio(RVFWLS/PASP)for evaluating systolic function of right ventricle(RV)in patients with hypertrophic cardiomyopathy(HCM).Methods Fifty-two HCM patients were retrospectively collected and divided into group A(RVFWLS/PASP≤0.75,n=26)and B(RVFWLS/PASP＞0.75,n=26)according to median RVFWLS/PASP.Meanwhile,26 healthy individuals were included as control group.Parameters of echocardiography and speckle tracking imaging(STI)were obtained and compared among 3 groups.The correlations of RVFWLS/PASP and other parameters were analyzed with linear regression.Results In group A and B,left ventricular ejection fraction(LVEF),RV septal longitudinal strain(RVSepLS),RVFWLS,RV end-diastolic volume index(RVEDVi),RV stroke volume(RVSV),RV fractional area change(RVFAC)and left ventricular global longitudinal strain(LVGLS)were all lower,while the ratio of peak E blood flow velocity at mitral orifice diastole to early mitral intervalal annulus diastole velocity(E/e′)were higher than those in control group(all adjusted P＜0.05).Compared with group B and control group,group A had higher PASP but lower RV ejection fraction(RVEF)(all adjusted P＜0.05).Furthermore,RVFWLS and LVGLS were both lower in group A than in group B(both adjusted P＜0.05).Linear regression analysis showed that RVSepLS and RVEF were independently linearly related to RVFWLS/PASP(both P＜0.05).Conclusion RVFWLS/PASP could be used to monitor changes of RV systoic function in HCM patients at early stage.
