Research advances on lipoprotein(a)in cerebrovascular diseases
10.3969/j.issn.1006-7795.2025.01.012
- VernacularTitle:脂蛋白a在脑血管病中的研究新进展
- Author:
Yibing GUO
1
;
Ran MENG
1
Author Information
1. 首都医科大学宣武医院神经内科,北京 100053
- Publication Type:Journal Article
- Keywords:
lipoprotein(a);
cerebrovascular diseases;
RNA-targeted therapies;
advances in clinical studies
- From:
Journal of Capital Medical University
2025;46(1):71-75
- CountryChina
- Language:Chinese
-
Abstract:
Lipoprotein(a)[Lp(a)]is a unique plasma lipoprotein particle with a distinct structure that has garnered significant research attention due to its strong association with various cerebrovascular diseases.Recent studies underscore elevated Lp(a)levels as a critical risk factor,with multiple Lp(a)-targeted therapies advancing through clinical trials.This review explores the structural,functional,and genetic features of Lp(a),its connection to cerebrovascular diseases,and the latest therapeutic strategies aimed at reducing its impact.By consolidating these advancements,we aim to provide new insights for Lp(a)-centered research and propose innovative approaches for cerebrovascular disease prevention and management.
