Study on risk factors of calf muscular venous thrombosis complicated with pulmonary embolism
10.3969/j.issn.1002-1671.2025.02.018
- VernacularTitle:小腿肌间静脉血栓并发肺栓塞的危险因素研究
- Author:
Mei ZHOU
1
;
Di KE
1
;
Yuan ZHENG
1
;
Feng LI
1
Author Information
1. 遵义医科大学附属医院放射科,贵州 遵义 563000
- Publication Type:Journal Article
- Keywords:
calf muscular venous thrombosis;
pulmonary embolism;
risk factors;
prediction model
- From:
Journal of Practical Radiology
2025;41(2):257-261
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the related risk factors for calf muscular venous thrombosis(CMVT)complicated with pulmonary embolism(PE),and to provide new theoretical basis for clinical diagnosis and treatment of CMVT patients.Methods A total of 200 CMVT patients were selected.CMVT patients with PE during hospitalization and within six months after discharge were selected as the PE group,and CMVT patients without PE were selected as the non-PE group.The differences in clinical data between the two groups were compared.Logistic regression analysis was performed to identify the independent factors of CMVT complicated with PE and to establish the clinical prediction model of CMVT complicated with PE.Results Among the 200 patients,36 cases were classified in the PE group,and 164 cases were classified in the non-PE group,resulting in an incidence rate of 18％.Logistic regression analysis indicated that"surgery","fracture",and"tumor"were identified as independent risk factors for developing PE in CMVT patients.Conversely,"anticoagulation"was a protective factor against PE in CMVT patients.Based on this,a regression equation model was established,with the predicted overall accuracy of 89.5％.The prediction model was analyzed using the Bootstrap resampling method,yielding an area under the curve(AUC)of 0.909 and a C-index of 0.908 7[95％confidence interval(CI)0.856 2-0.961 2].These results indicated that the prediction model exhibited superior discriminatory ability in distinguishing between patients with PE and those without.Conclusion Surgery,fracture,and tumor are independent risk factors for PE in patients with CMVT.Anticoagulant therapy is recommended for preventing complications such as PE in cases of CMVT.The constructed clinical prediction model of CMVT complicated with PE can provide reference for the treatment and prognosis of CMVT patients.
