Research progress of transcranial alternating current stimulation in the treatment of Alzheimer's disease
10.3969/j.issn.1004-1648.2025.01.016
- VernacularTitle:经颅交流电刺激治疗Alzheimer's病的研究进展
- Author:
Shuang FANG
1
;
Longjie QU
1
;
Yun XU
1
Author Information
1. 210008 南京医科大学附属鼓楼临床医学院
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
transcranial alternating current stimulation;
cognitive and memory function;
psychiatric symptoms;
sleep quality
- From:
Journal of Clinical Neurology
2025;38(1):65-69
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease(AD)is the most common neurodegenerative disorder leading to dementia in the elderly,characterized by a gradual decline in cognitive function and daily living abilities.The pathogenesis of AD remains unclear,and the efficacy of existing pharmacological treatments is limited,making the search for new therapeutic approaches imperative.Current research suggests that transcranial alternating current stimulation(tACS)can ameliorate cognitive deficits in AD,potentially due to its ability to modulate single or nested brain rhythms,local or distant synchronization,and metabolic activity,which can influence cognitive functions.This review summarizes the research progress of tACS in the treatment of AD,aiming to provide new insights into the exploration of the pathogenesis and treatment of AD.
