Evaluation and improvement of liver reserve function before hepatectomy for perihilar cholangiocarcinoma

VernacularTitle:肝门部胆管癌术前预留肝叶储备功能的评估与改善
Author: Ming XIAO ¹ ; Canhong XIANG
Author Information

1. 山东大学第二医院肝胆外科,山东济南 250033;清华大学附属北京清华长庚医院肝胆胰中心/清华大学临床医学院数智肝胆病学教育部重点实验室,北京102218
Publication Type:Journal Article
Keywords: Klatskin Tumor; Liver Regeneration; Liver Reserve; Portal Vein Embolization
From: Chinese Journal of General Surgery 2024;33(12):1958-1966
CountryChina
Language:Chinese
Abstract: Perihilar cholangiocarcinoma (PHCC) is the most common type of cholangiocarcinoma and poses a serious threat to the life and health of the Chinese population. PHCC is often accompanied by bile stasis,abnormal hepatocyte metabolism within the hepatic lobules,and varying degrees of liver dysfunction. Additionally,systemic organs such as the kidneys and intestines are affected,leading to a higher risk of liver resection surgery for these patients. Currently,clinical methods are unable to accurately assess the regional liver reserve function in such patients,and many issues in assessment strategies remain unclear and unresolved. On the other hand,the strategies and efficacy of promoting hypertrophy of the future liver remnant before liver resection remain controversial. This article addresses these two issues,discussing their definitions,characteristics,and recent progress in detail.