Attention impairment in patients with temporal lobe epilepsy
10.3760/cma.j.cn371468-20241023-00503
- VernacularTitle:颞叶癫痫患者注意力损伤
- Author:
Qianqian JI
1
;
Pei LI
;
Xijun LI
;
Kejing LI
;
Denghong MA
Author Information
1. 青海大学研究生院，西宁 810000
- Publication Type:Journal Article
- Keywords:
Temporal lobe epilepsy;
Attention impairment;
Neuroelectrophysiology;
Neuroimaging;
Treatment
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2025;34(3):283-288
- CountryChina
- Language:Chinese
-
Abstract:
Attention impairment in temporal lobe epilepsy (TLE) leads to other advanced cognitive impairments, such as memory and emotional recognition. Moreover, the severity of attention impairment determine the differences in strategies for preventing sudden unexpected death in epilepsy (SUDEP). Factors such as abnormal brain electrical discharges, sleep, and antiepileptic drugs are all associated with attention impairment. Neuroelectrophysiological observations have shown that abnormal electrical discharges interfere with the synchronization of cortical oscillations, and preventing the spread of abnormal epileptic discharges to subcortical activation structures helps reduce attention disorders. Neuroimaging reveals damage to the gray matter and white matter of the brain related to attention and poor connectivity of the whole-brain network. Therefore, early identification of attention impairment in TLE patients has become even more important. Treatment of attention impairment includes supplementing attention-related neurotransmitters, cognitive-behavioral therapy, surgical procedures, and neuromodulation techniques. This article mainly reviews the characteristics of attention impairment in TLE patients from the perspectives of clinical behavior, pathophysiology, and treatment, aiming to provide new insights for the early identification and management of attention impairment in TLE patients.
