Anxiety and quality of life in patients with hematologic malignancy: the mediating role of resilience and the moderating role of self-efficacy
10.3760/cma.j.cn371468-20240318-00117
- VernacularTitle:恶性血液肿瘤患者焦虑情绪与生命质量：心理弹性的中介作用和自我效能感的调节作用
- Author:
Limin ZHANG
1
;
Xiuzhen ZHANG
;
Chuanxin LIU
Author Information
1. 济宁医学院精神卫生学院，济宁 272067
- Publication Type:Journal Article
- Keywords:
Haematological malignancies;
Anxiety;
Resilience;
Self-efficacy;
Quality of life
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2024;33(12):1099-1105
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the correlation between anxiety and quality of life in patients with hematologic malignancy, and the role of resilience and self-efficacy in it.Methods:From February to June 2017, a total of 284 patients with hematologic malignancy were surveyed by general information questionnaire, self-rating anxiety scale (SAS), Connor-Davidson resilience scale(CD-RISC), general self-efficacy scale (GSES), and cancer quality of life questionnaires-core 30 (EORTC QLQ-C30). SPSS 25.0 software was used to conduct common method bias testing, independent sample t-test and Pearson correlation analysis, and PROCESS 3.4 macro program was used to test the mediating and moderating effects. Results:(1) The quality of life score among hematologic malignancy patients (72.52±19.18) was significantly lower than the norm (78.97) ( t=-5.669, P<0.01). (2) Anxiety (43.71±11.22) was significantly negatively correlated with resilience (69.96±15.32), self-efficacy (22.93±6.04), and quality of life (72.52±19.18) ( r=-0.232, -0.119, -0.236, all P<0.05). There were significant positive correlations between resilience, self-efficacy and quality of life ( r=0.113, 0.210, 0.652, all P<0.05). (3) Anxiety played a significant negatively predictive effect on quality of life in patients with hematologic malignancy ( β=-0.233, t=-4.032, P<0.01). Resilience partially mediated the relationship between anxiety and quality of life. The direct effect and the mediating effect accounted for 82.40% (-0.192/-0.233) and 17.60% (-0.041/-0.233) of the total effects respectively. Self-efficacy played a moderating role between resilience and quality of life. For the low self-efficacy group, resilience could not predict quality of life ( βsimple =0.059, t=0.650, P>0.05, 95% CI=-0.119-0.236). For the high self-efficacy group, resilience had a significant positively predictive effect on quality of life ( βsimple =0.313, t=3.390, P<0.01, 95% CI=0.131-0.494). Conclusion:Anxiety in patients with hematologic malignancy can directly or indirectly affect quality of life through resilience, and this mediating model is moderated by self-efficacy.
