Recovery after laparoscopic surgery in obese patients with gastrointestinal tumors: a prospective propensity score-matched cohort study
10.3760/cma.j.cn115822-20241011-00185
- VernacularTitle:肥胖型胃肠肿瘤患者腹腔镜手术后恢复状况：基于倾向性评分匹配的前瞻性队列研究
- Author:
Jing ZHOU
1
;
Xiao LIU
1
;
Xuefen CHEN
1
;
Chen CHEN
1
;
Wenquan LIANG
1
Author Information
1. 解放军总医院第一医学中心普通外科医学部，北京 100853
- Publication Type:Journal Article
- Keywords:
Gastrointestinal tumor;
Obesity;
Body composition;
Postoperative recovery;
Complications
- From:
Chinese Journal of Clinical Nutrition
2025;33(5):357-363
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the body composition of patients diagnosed with malignant gastrointestinal tumors and to assess the impact of obesity on surgical outcomes and postoperative recovery following laparoscopic radical surgery.Methods:Patients with malignant gastrointestinal tumors who underwent laparoscopic surgery in the Department of General Surgery at the First Medical Center of the Chinese PLA General Hospital from February to October 2023 were prospectively enrolled. The body composition was measured by bioelectrical impedance analysis. Accordingly, the obese patients were selected as the obese group, while non-obese patients entered the control group using propensity score matching. The clinical data, in particular the postoperative recovery, were compared between these two groups.Results:A total of 593 patients with malignant gastrointestinal tumors were included in the analysis, including 108 patients in the obese group and 107 in the control group. The two groups significantly differed in the six minute walking test ( P=0.003), postoperative anemia ( P=0.036), white blood cell count ( P<0.001), neutrophil percent ( P<0.001), and neutrophil-to-lymphocyte ratio (NLR) ( P=0.001). The obese group exhibited a significntly higher risk of developing complications after surgery ( P=0.039). Conclusions:Obese patients with malignant gastrointestinal tumors are more likely to experience complications such as muscle weakness, anemia, infection, and inflammation after a laparoscopic radical surgery. Close monitoring and proactive perioperative interventions should be taken to mitigate such risks.
