A systematic review of validation studies on the performance of GLIM criteria for malnutrition assessment
10.3760/cma.j.cn115822-20241204-00225
- VernacularTitle:GLIM营养不良诊断标准验证性研究的系统评价
- Author:
Yongshuai MENG
1
;
Yanjuan LU
;
Chunlei LIU
;
Huilin JIA
;
Mengying SUN
;
Xiaoge HE
;
Xiaoya SHENG
;
Linna ZHANG
;
Yinan MA
;
Sangsang KE
;
Lichuan ZHANG
;
Qian LU
Author Information
1. 河北大学护理学院，保定 071000
- Publication Type:Journal Article
- Keywords:
Nutritional diagnosis;
Malnutrition;
GLIM;
Clinical outcomes;
Validity
- From:
Chinese Journal of Clinical Nutrition
2025;33(4):290-298
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate studies validating the performance of the Global Leadership Initiative on Malnutrition (GLIM) in diagnosing malnutrition.Methods:Seven Chinese and English databases including Embase, Web of Science (WOS), PubMed, CINAHL, Cochrane Library, SinoMed, CNKI, Wanfang Data, and VIP Database were searched for articles on the validation of GLIM criteria published between September 2018 and September 2024. Two researchers independently performed literature screening and data extraction. The concurrent and predictive validity of the criteria was analyzed.Results:A total of 136 papers were included for analysis. The GLIM criteria for diagnosing malnutrition had a sensitivity of 77%, a specificity of 87%, and an area under the curve (AUC) of 0.90. Malnutrition diagnosed by the GLIM criteria predicted prolonged hospital and intensive care unit (ICU) stays, increased readmission and complication rates (both overall and infectious), reduced survivals (median, overall, and disease-free), and increased in-hospital and follow-up mortalities. Both moderate and severe malnutrition predicted decreased overall survival. However, only three studies analyzed the impact of nutritional therapy on the clinical outcomes of malnourished patients.Conclusions:The GLIM criteria accurately differentiate malnutrition and are a valid predictive tool of clinical outcomes. However, the validity criteria in these validation studies were questionable, along with high methodological heterogeneity. Furthermore, there is a lack of studies validating the role of nutritional therapy in improving the clinical outcomes of malnourished patients.
