Comprehensive evaluation of compound trace element preparations used in Beijing
10.3760/cma.j.cn115822-20240724-00133
- VernacularTitle:北京地区复合微量元素制剂的综合评价
- Author:
Na YANG
1
;
Han LIU
;
Yan XING
;
Rongrong LI
;
Fang LIU
;
Guang YANG
;
Xiaoxiao LI
Author Information
1. 北京大学第三医院药学部，北京 100191
- Publication Type:Journal Article
- Keywords:
Trace element;
Parenteral nutrition;
Comprehensive evaluation
- From:
Chinese Journal of Clinical Nutrition
2025;33(2):98-104
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the types and contents of trace elements in compound trace element preparations used in parenteral nutrition in Beijing against the doses recommended by the guidelines, so as to facilitate optimal choice of preparations for different populations in clinical practice.Methods:The available compound trace element preparations were determined according to the drug list from the Medical Insurance Recruitment and Procurement System of Beijing and the recommended doses of trace elements in the guidelines released by Chinese domestic and foreign nutrition societies were collected and compared.Results:The compound trace element preparations used in Beijing comprised 4 varieties and 6 specifications, with the daily cost ranging from 11.32 to 471 Chinese Yuan. There were 3 varieties of trace element preparations for adults, including multi-trace elements injection (Ⅱ), multi-trace elements injection (Ⅲ), and multi-trace elements injection. Among those, multi-trace elements injection (Ⅲ) met the guideline recommendations best and the price was moderate. For pediatric populations, multi-trace elements injections (Ⅰ) satisfied better the trace element requirements for preterm infants and infants from term to 3 months, while multi-trace elements injections (Ⅲ) outperformed in meeting the trace element requirements for 3-to-12-month infants and children. However, there were still some differences in the trace element contents between the two preparations and the guideline recommendations.Conclusion:The currently available varieties and specifications of trace element preparations basically meet the recommendations of evidence-based guidelines, but there is still the need to improve the instructions for and evidence on the pediatric application of certain preparations.
