Reflections on the current state of diagnosis and treatment for peritoneal metastasis in colorectal cancer
10.3760/cma.j.cn441530-20250308-00090
- VernacularTitle:对结直肠癌腹膜转移诊治现状的思考
- Author:
Jian WANG
1
;
Xiangui HE
1
;
Yeting HU
1
;
Lifeng SUN
1
;
Kefeng DING
1
Author Information
1. 浙江大学医学院附属第二医院大肠外科 恶性肿瘤预警与干预教育部重点实验室 消化系统肿瘤医药基础研究创新中心（教育部），杭州 310009
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Peritoneal metastasis;
Diagnosis;
Treatment
- From:
Chinese Journal of Gastrointestinal Surgery
2025;28(5):465-472
- CountryChina
- Language:Chinese
-
Abstract:
Peritoneal metastasis of colorectal cancer is the second most common metastatic pattern after liver metastasis, clinically common and associated with a poor prognosis. Refractory subtypes such as mucinous adenocarcinoma, signet-ring cell carcinoma, and BRAF V600E-mutated colorectal cancers account for a relatively high proportion in peritoneal metastasis. While previous diagnosis and treatment faced significant challenges, recent advances in new technologies and evolving therapeutic concepts have achieved progress in management. Many patients with colorectal cancer peritoneal metastasis have obtained favorable treatment outcomes, though numerous challenges persist. This article provides an in-depth analysis of current status and advancements in the diagnosis and treatment of colorectal cancer peritoneal metastasis, examines existing clinical difficulties and unresolved issues, and explores the application of advanced technologies in clinical practice. Through promoting individualized, precise, and standardized treatment concepts, we aim to enhance survival benefits for more patients.
