Clinical value and implementation strategies of normothermic intraperitoneal and systemic chemotherapy (NIPS) in the treatment of gastric cancer with peritoneal metastasis
10.3760/cma.j.cn441530-20250308-00110
- VernacularTitle:腹腔内常温联合全身治疗（NIPS）应用于胃癌腹膜转移的临床价值和实施策略
- Author:
Chao YAN
1
;
Sheng LU
1
;
Zhenggang ZHU
1
Author Information
1. 上海交通大学医学院附属瑞金医院普通外科 上海消化外科研究所 上海市胃肿瘤重点实验室，上海 200025
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Peritoneal metastasis;
Intraperitoneal chemotherapy;
Intraperitoneal chemotherapy port;
Conversion surgery
- From:
Chinese Journal of Gastrointestinal Surgery
2025;28(5):481-486
- CountryChina
- Language:Chinese
-
Abstract:
Peritoneal metastasis of gastric cancer is a common metastatic form in advanced gastric cancer, and conventional systemic chemotherapy has shown unsatisfactory efficacy. This article systematically examines the clinical value and implementation strategies of normothermic intraperitoneal chemotherapy and systemic therapy (NIPS) in the treatment of gastric cancer peritoneal metastasis. It covers aspects such as the precise selection of treatment candidates, optimization of drug regimens, standardized management of intraperitoneal chemotherapy ports, determination of the appropriate timing for conversion surgery, and postoperative treatment optimization. The aim is to provide scientific guidance for the clinical application of NIPS, promote its standardization, and improve the prognosis for patients with gastric cancer peritoneal metastasis.
