Prognostic value of CT combined with DCE-MRI parameters in predicting poor short-term prognosis of patients with colorectal cancer after radical surgery
10.3760/cma.j.cn115807-20241226-00392
- VernacularTitle:CT结合DCE-MRI参数对结直肠癌根治术后患者短期预后不良的预测价值
- Author:
Ning ZHANG
1
;
Yong WANG
;
Xiaoyu GAO
;
Lin WANG
;
Haiqing YANG
;
Yinghao HAO
Author Information
1. 河北医科大学第二医院医学影像科，石家庄 050000
- Publication Type:Journal Article
- Keywords:
Colorectal cancer;
Electronic computed tomography;
Dynamic enhanced magnetic resonance imaging
- From:
Chinese Journal of Endocrine Surgery
2025;19(2):271-275
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the predictive value of computed tomography (CT) combined with dynamic enhanced magnetic resonance imaging (DCE-MRI) parameters in patients with colorectal cancer after radical surgery.Methods:A total of 180 patients with colorectal cancer admitted to the Second Hospital of Hebei Medical University from Dec. 2021 to Dec. 2023 were retrospectively selected as the study objects. All patients were treated with radical resection of colorectal cancer and followed up for 12 months. They were divided into good prognosis group ( n=129) and poor prognosis group ( n=51) according to whether tumor recurrence and metastasis occurred. All patients were examined by CT and DCE-MRI. Clinical data, CT and DCE-MRI parameters were compared between the two groups. Cox regression was used to analyze the influencing factors of short-term adverse prognosis in patients with colorectal cancer, and ROC curve was drawn to analyze the value of SUV max, K trans, K ep and Ve in single or combined prediction of short-term adverse prognosis in patients with colorectal cancer. Results:SUV max, K trans, K ep and Ve in the poor prognosis group were higher than those in the good prognosis group ( P<0.05) . Cox regression analysis showed that high levels of SUV max ( HR=2.818, 95% CI= 1.808-4.393) , K trans ( HR=516.829, 95% CI=6.745-30603.733) , K ep ( HR=117.756, 95% CI= 4.598-3015.614) and Ve ( HR=9453.000, 95% CI= 63.534-1406482.337) were independent risk factors for short-term adverse prognosis in patients with colorectal cancer ( P<0.05) . The AUC value of SUVmax, K trans, K ep and Ve combined predicted short term adverse prognosis in colorectal cancer patients was higher than that of single detection ( Z=3.126, 4.359, 4.368, 3.987, P<0.05) . Conclusion:CT combined with DCE-MRI parameters have high predictive value for short term poor prognosis of patients with colorectal cancer after radical surgery.
