Relationship between serum levels of SC and SV and insulin resistance in elderly gestational diabetes mellitus
10.3760/cma.j.cn115807-20231011-00103
- VernacularTitle:血清SC、SV水平与高龄妊娠期糖尿病患者胰岛素抵抗的关系
- Author:
Hua XU
1
;
Haijing YU
1
;
Xueli GAO
1
;
Qian WU
1
;
Xiaoli WANG
1
Author Information
1. 烟台毓璜顶医院产科 264000
- Publication Type:Journal Article
- Keywords:
Gestational diabetes mellitus;
Visfatin;
Chemerin;
Insulin resistance
- From:
Chinese Journal of Endocrine Surgery
2025;19(3):353-356
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study on the relationship between serum levels of SC and SV and insulin resistance in elderly gestational diabetes mellitus.Methods:120 elderly patients with GDM were treated in Obstetrics Department of Yantai Yuhuangding Hospital from Jun. 2019 to Jun. 2021. The healthy women (58 cases) and normal pregnant women (58 cases) were selected as the control group at the same time, and the clinical data and serum samples of subjects were collected. The levels of serum SC, SV, FPG and HbAlc were measured, the HOMA-IR of the aged GDM was calculated, and the difference of serum index expression among the subjects in each group was analyzed. The relationship between serum SC, SV and insulin resistance was analyzed by Person correlation, and the risk factors of GDM were analyzed by Logistic regression.Results:: There was significant difference in HbAlc, HOMA-IR, FPG, SC, and SV among the three groups. The levels of each index in the elderly GDM group were significantly higher than those in the normal pregnancy group and the healthygroup ( P<0.05). Pearson analysis showed that SC ( P=0.558, 0.626, 0.672), SV ( P=0.576, 0.663, 0.696) was positively correlated with HbAlc, HOMA-IR, FPG in elderly patients with GDM ( P<0.001). Logistic regression analysis showed that SC, SV was risk factors for GDM in elderly pregnant women. Conclusion:There is a positive correlation between serum SC, SV level and insulin resistance, which are risk factors for GDM in elderly pregnant women.
