Ultrasound-guided quadratus lumborum block combined with general anesthesia in laparoscopic hysterectomy and its effect on inflammation and oxidative stress response of patients
10.3760/cma.j.cn115807-20231227-00206
- VernacularTitle:超声引导下腰方肌阻滞联合全身麻醉在腹腔镜子宫切除术中应用效果
- Author:
Dongfeng MA
1
;
Guixiang GUO
;
Lei ZHANG
;
Yu LI
;
Fuyu TIAN
;
Xinli HUANG
;
Meilin AN
Author Information
1. 廊坊市人民医院麻醉科，廊坊 065000
- Publication Type:Journal Article
- Keywords:
Adenomyosis;
Laparoscopic hysterectomy;
Ultrasound guidance;
Quadratus lumborum block;
Transversus abdominis plane block;
General anesthesia
- From:
Chinese Journal of Endocrine Surgery
2024;18(6):898-902
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the application of ultrasound-guided quadratus lumborum block (QLB) combined with general anesthesia in laparoscopic hysterectomy (LH) and its effect on inflammation and oxidative stress response of patients.Methods:Patients with adenomyosis who underwent surgery to minimize LH in Langfang People’s Hospital from Jan. 2021 to Dec. 2023 were collected as the study subjects. They were divided into two groups according to the random number table method, 53 cases each. The control group were given general anesthesia, and the observation group were given ultrasound-guided QLB+general anesthesia. The recovery and postoperative recovery indexes (recovery, spontaneous breathing recovery, removal of laryngeal mask, first getting out of bed, exhaust time), opioid dosage, remedial analgesia times and first pressing analgesia pump time were counted and compared between the two groups. The pain numerical rating scale (NRS) scores of the two groups at different time points (2, 6, 12, 24 h after operation) were compared. The incidence of adverse reactions during hospitalization was counted and compared between the two groups.Results:The time of awakening, spontaneous breathing recovery, removal of laryngeal mask, first getting out of bed and exhaust in the observation group were shorter than those in the control group ( P < 0.05). The total dosage of remifentanil in the observation group was less than that in the control group, the number of remedial analgesia was lower than that in the control group, and the time of first pressing analgesia pump was longer than that in the control group ( P<0.05). At 6, 12 and 24 h after operation, the NRS scores in resting and active state were higher than those at 2 h after operation. The NRS scores in resting and active state at 24 h after operation were lower than those at 12 h after operation, showing a trend of rising first and then decreasing. The NRS scores in resting and active state in the observation group were lower than those in the control group ( P<0.05). The adverse reaction rate of the two groups was compared ( P> 0.05) . Conclusion:Ultrasound-guided QLB combined with general anesthesia can effectively improve the recovery of LH patients, promote postoperative recovery, relieve postoperative pain, and reduce the dose of opioids.
