Effects of Sitting Baduanjin Combined with Sacubitril/Valsartan on Cardiopulmonary Function,Exercise Capacity and Vascular Endothelial Function in Patients with Coronary Heart Disease after PCI
10.13241/j.cnki.pmb.2025.19.006
- VernacularTitle:坐式八段锦联合沙库巴曲缬沙坦对冠心病患者PCI术后心肺功能、运动能力及血管内皮功能的影响
- Author:
Xiang-hua CHEN
1
;
Ya-ting LI
1
;
Xiao-lan LIN
1
Author Information
1. 漳州市第三医院心脏与血管介入医学科 福建漳州 363005
- Publication Type:Journal Article
- Keywords:
Sacubitril/Valsartan;
Sitting Baduanjin;
Coronary heart disease;
Percutaneous coronary intervention;
Cardiopulmonary function;
Exercise capacity;
Vascular endothelial function
- From:
Progress in Modern Biomedicine
2025;25(19):3077-3083,3121
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effects of Sitting Baduanjin combined with Sacubitril/Valsartan on cardiopulmonary function,exercise capacity and vascular endothelial function in patients with coronary heart disease after percutaneous coronary intervention(PCI).Methods:A retrospective analysis was conducted on the clinical data of 86 patients with coronary heart disease who underwent percutaneous coronary intervention(PCI)at Zhangzhou Third Hospital from April 2023 to August 2024,among these patients,43 were treated with a combination of Sacubitril/Valsartan and Sitting Baduanjin,forming the study group,the other 43 patients,treated with sacubitril/valsartan alone,were randomly assigned in a 1∶1 ratio to form the control group.The cardiopulmonary function[cardiac index(CI),left ventricular ejection fraction(LVEF),The ratio of forced expiratory volume to forced vital capacity(FEV/FVC),maximum ventilation volume(MVV)].Exercise capacity[6-minute walking test distance(6MWD),maximum motion load(MWL),peak oxygen uptake(VO2peak)],vascular endothelial function[endothelin-1(ET-1),vascular endothelium-dependent diastolic function(FMD),vascular pseudohematologic factor(vWF)]and the occurrence of adverse cardiovascular events between the two groups were compared.Results:CI,LVEF,FEV/FVC and MVV of the study group at 2 months after intervention were higher than those of the control group(P＜0.05).6MWD,MWL,VO2peak of the study group at 2 months after intervention were higher than those of the control group(P＜0.05).ET-1,vWF of the study group at 2 months after intervention were lower than those of the control group,FMD was higher than that of the control group(P＜0.05).There was no significant difference in the total incidence of adverse cardiovascular events between the two groups(P＞0.05).Conclusion:Sitting Baduanjin combined with Sacubitril/Valsartan can effectively improve the cardiopulmonary function,exercise capacity and vascular endothelial function of patients with coronary heart disease after PCI.
